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Dietary Lipid Intervention in the Prevention of Brain Aging

Wei Xiong,Bing Fang,Xiaoyu Wang,Ming Zhang,Min Du,Jiazeng Sun,Juan Chen,Yixuan Li,Changhao Sun,Xingen Lei,Xue Zhang,Fazheng Ren,

Engineering doi: 10.1016/j.eng.2023.04.012

Abstract: As people live longer, the burden of aging-related brain diseases, especially dementia, is increasing. Brain aging increases the risk of cognitive impairment, which manifests as a progressive loss of neuron function caused by the impairment of synaptic plasticity via disrupting lipid homeostasis. Therefore, supplemental dietary lipids have the potential to prevent brain aging. This review summarizes the important roles of dietary lipids in brain function from both structure and mechanism perspectives. Epidemiological and animal studies have provided evidence of the functions of polyunsaturated fatty acids (PUFAs) in brain health. The results of interventions indicate that phospholipids—including phosphatidylcholine, phosphatidylserine, and plasmalogen—are efficient in alleviating cognitive impairment during aging, with plasmalogen exhibiting higher efficacy than phosphatidylserine. Plasmalogen is a recognized nutrient used in clinical trials due to its special vinyl ether bonds and abundance in the postsynaptic membrane of neurons. Future research should determine the dose-dependent effects of plasmalogen in alleviating brain-aging diseases and should develop extraction and storage procedures for its clinical application.

Keywords： Brain aging     Nutritional intervention     Phospholipids     Phosphatidylcholine     Phosphatidylserine     Plasmalogen    

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Plasma transthyretin is a nutritional biomarker in human morbidities

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 540-550 doi: 10.1007/s11684-022-0940-3

Abstract: Transthyretin (TTR) is a small liver-secreted plasma protein that shows close correlations with changes in lean body mass (LBM) during the entire human lifespan and agglomerates the bulk of nitrogen (N)-containing substrates, hence constituting the cornerstone of body building. Amino acids (AAs) dietary restriction causes inhibition of TTR production and impairs the accretion of LBM reserves. Inflammatory disorders result in cytokine-induced abrogation of TTR synthesis and urinary leakage of nitrogenous catabolites. Taken together, the data indicate that malnutrition and inflammation may similarly suppress the production of TTR through distinct and unrelated pathophysiological mechanisms while operating in concert to downsize LBM stores. The hepatic synthesis of TTR integrates both machineries, acting as a marker of reduced LBM resources still available for defense and repair processes. TTR operates as a universal surrogate analyte that allows for the grading of residual LBM capacity to reflect disease burden. Measurement of TTR is a simple, rapid, and inexpensive micro-method that may be reproduced on a daily basis, hence ideally suited for the follow-up of the most intricated clinical situations and as a reliable predictor of any morbidity outcome.

Keywords： lean body mass     nutritional status     transthyretin     malnutrition     inflammation     amyloidosis    

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USING NUTRITIONAL STRATEGIES TO MITIGATE RUMINAL METHANE EMISSIONS FROM RUMINANTS

Frontiers of Agricultural Science and Engineering 2023, Volume 10, Issue 3,   Pages 390-402 doi: 10.15302/J-FASE-2023504

Abstract:

● Microbial fermentation in the rumen is a main source of methane emissions.

Keywords： nutritional strategy     mitigation     microbe     methane     ruminant    

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The early percutaneous coronary intervention in elderly patients with acute coronary syndrome

HUANG Xiong, CAO Xuebin, ZHANG Gang

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 15-18 doi: 10.1007/s11684-008-0004-3

Abstract: It is challenging to undo early percutaneous intervention (PCI) in the elderly with acute coronary syndromeAll the patients had early percutaneous coronary intervention and were followed up for 6–12 months by

Keywords： door-to-balloon     percutaneous intervention     coronary syndrome     angioplasty     successful    

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Ultrasound-guided prostate percutaneous intervention robot system and calibration by informative particle

Frontiers of Mechanical Engineering 2022, Volume 17, Issue 1,   Pages 3-3 doi: 10.1007/s11465-021-0659-x

Abstract: Applying a robot system in ultrasound-guided percutaneous intervention is an effective approach for prostate

Keywords： ultrasound image guidance     prostate percutaneous intervention     parallel robot     kinematics identification    

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Drug-coated balloon-only strategy for percutaneous coronary intervention of left main coronary artery

Frontiers of Medicine 2023, Volume 17, Issue 1,   Pages 75-84 doi: 10.1007/s11684-022-0950-1

Abstract: single-center registry study included all consecutive patients who underwent percutaneous coronary intervention

Keywords： drug-coated balloon     left main     high bleeding risk     predilatation     calcifield lesion     percutaneous coronary intervention    

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Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy

Maliwan NACONSIE,Peng ZHANG

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 4,   Pages 285-294 doi: 10.15302/J-FASE-2016119

Abstract: Genetic engineering provides promising approaches to improve nutritional value and increase resistance

Keywords： Manihot esculenta     protein enhancement     RNA interference     transgenesis     virus resistance    

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Molecular network-based intervention brings us closer to ending the HIV pandemic

Xiaoxu Han, Bin Zhao, Minghui An, Ping Zhong, Hong Shang

Frontiers of Medicine 2020, Volume 14, Issue 2,   Pages 136-148 doi: 10.1007/s11684-020-0756-y

Abstract: populations, reconstruct the history of HIV spread, monitor the dynamics of HIV transmission, guide targeted intervention

Keywords： human immunodeficiency virus type 1     molecular cluster     transmission cluster     risk network     targeted intervention    

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Autophagy and the nutritional signaling pathway

Long HE,Shabnam ESLAMFAM,Xi MA,Defa LI

Frontiers of Agricultural Science and Engineering 2016, Volume 3, Issue 3,   Pages 222-230 doi: 10.15302/J-FASE-2016106

Abstract: During their growth and development, animals adapt to tremendous changes in order to survive. These include responses to both environmental and physiological changes and autophagy is one of most important adaptive and regulatory mechanisms. Autophagy is defined as an autolytic process to clear damaged cellular organelles and recycle the nutrients via lysosomic degradation. The process of autophagy responds to special conditions such as nutrient withdrawal. Once autophagy is induced, phagophores form and then elongate and curve to form autophagosomes. Autophagosomes then engulf cargo, fuse with endosomes, and finally fuse with lysosomes for maturation. During the initiation process, the ATG1/ULK1 (unc-51-like kinase 1) and VPS34 (which encodes a class III phosphatidylinositol (PtdIns) 3-kinase) complexes are critical in recruitment and assembly of other complexes required for autophagy. The process of autophagy is regulated by autophagy related genes (ATGs). Amino acid and energy starvation mediate autophagy by activating mTORC1 (mammalian target of rapamycin) and AMP-activated protein kinase (AMPK). AMPK is the energy status sensor, the core nutrient signaling component and the metabolic kinase of cells. This review mainly focuses on the mechanism of autophagy regulated by nutrient signaling especially for the two important complexes, ULK1 and VPS34.

Keywords： Autophagy     ULK1 complex     VPS34 complex     AMPK     mTOR     nutrient signaling    

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The Nutritional Support After Liver Transplantation

Fei Jia,Leng Xisheng,Peng Jirun

Strategic Study of CAE 2003, Volume 5, Issue 12,   Pages 24-29

Abstract:

The nutritional state of the recipient of liver transplantation, the determination and the correctionof the nutritional state before surgery, the function of the liver graft, the principle and practiceof the nutritional support after surgery and the nutritional support in child undergone transplantation

Keywords： liver transplantation     after surgery     nutritional support    

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Expression of integrin in hepatic fibrosis and intervention of resveratrol

Jianye WU, Chuanyong GUO, Jun LIU, Xuanfu XUAN

Frontiers of Medicine 2009, Volume 3, Issue 1,   Pages 100-107 doi: 10.1007/s11684-009-0013-x

Abstract: this study was to explore the expression of integrin-β1 in different stages of hepatic fibrosis and intervention

Keywords： liver fibrosis     integrin-β1     resveratrol     tumor growth factor-β     tissue inhibitor of metalloproteinase-1    

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Foxtail millet: nutritional and eating quality, and prospects for genetic improvement

Lu HE,Bin ZHANG,Xingchun WANG,Hongying LI,Yuanhuai HAN

Frontiers of Agricultural Science and Engineering 2015, Volume 2, Issue 2,   Pages 124-133 doi: 10.15302/J-FASE-2015054

Abstract: It also has high nutritional value.

Keywords： foxtail millet     grain quality     quality evaluation     breeding for quality    

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Achievements in burn surgery over the past 50 years in China

WANG Shiliang

Frontiers of Medicine 2008, Volume 2, Issue 4,   Pages 332-336 doi: 10.1007/s11684-008-0063-5

Abstract: burns, resuscitation, anti-infection, prevention and cure of internal organ injuries, metabolic and nutritional

Keywords： immunology     scientific     nutritional     microbiology     engineering    

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Managing soil quality for humanity and the planet

Rattan LAL

Frontiers of Agricultural Science and Engineering 2020, Volume 7, Issue 3,   Pages 251-253 doi: 10.15302/J-FASE-2020329

Abstract:

Rather than a human-centric, the basic strategy of achieving Sustainable Development Goals must be focused on restoring and sustaining planetary processes. The urgency of meeting the demands of the humanity must be reconciled with the necessity of enhancing the environment. Increasing and restoring soil organic matter content of the degraded and depleted soils is critical to strengthening planetary processes.

Keywords： soil quality     humanity     planet     climate change     soil carbon sequestration     food and nutritional security    

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Micro-Intervention Rural Planning Based on Cultural Heritance

Guo Haian

Strategic Study of CAE 2019, Volume 21, Issue 2,   Pages 27-33 doi: 10.15302/J-SSCAE-2019.02.019

Abstract: The micro-intervention planning theory is a cultural-guided planning strategy for rural revival, where

Keywords： rural planning     micro-intervention planning     consequential     fault-tolerant     rural culture     rural revival    

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Title Author Date Type Operation

Dietary Lipid Intervention in the Prevention of Brain Aging

Wei Xiong,Bing Fang,Xiaoyu Wang,Ming Zhang,Min Du,Jiazeng Sun,Juan Chen,Yixuan Li,Changhao Sun,Xingen Lei,Xue Zhang,Fazheng Ren,

Journal Article

Plasma transthyretin is a nutritional biomarker in human morbidities

Journal Article

USING NUTRITIONAL STRATEGIES TO MITIGATE RUMINAL METHANE EMISSIONS FROM RUMINANTS

Journal Article

The early percutaneous coronary intervention in elderly patients with acute coronary syndrome

HUANG Xiong, CAO Xuebin, ZHANG Gang

Journal Article

Ultrasound-guided prostate percutaneous intervention robot system and calibration by informative particle

Journal Article

Drug-coated balloon-only strategy for percutaneous coronary intervention of left main coronary artery

Journal Article

Transgenic technologies in cassava for nutritional improvement and viral disease resistance: a key strategy

Maliwan NACONSIE,Peng ZHANG

Journal Article

Molecular network-based intervention brings us closer to ending the HIV pandemic

Xiaoxu Han, Bin Zhao, Minghui An, Ping Zhong, Hong Shang

Journal Article

Autophagy and the nutritional signaling pathway

Long HE,Shabnam ESLAMFAM,Xi MA,Defa LI

Journal Article

The Nutritional Support After Liver Transplantation

Fei Jia,Leng Xisheng,Peng Jirun

Journal Article

Expression of integrin in hepatic fibrosis and intervention of resveratrol

Jianye WU, Chuanyong GUO, Jun LIU, Xuanfu XUAN

Journal Article

Foxtail millet: nutritional and eating quality, and prospects for genetic improvement

Lu HE,Bin ZHANG,Xingchun WANG,Hongying LI,Yuanhuai HAN

Journal Article

Achievements in burn surgery over the past 50 years in China

WANG Shiliang

Journal Article

Managing soil quality for humanity and the planet

Rattan LAL

Journal Article

Micro-Intervention Rural Planning Based on Cultural Heritance

Guo Haian

Journal Article